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Medical
Resources :: Common Diseases :: Infectious
Diseases & Parasites :: TB and Other Infectious Diseases
Prevalence of infection with Mycobacterium tuberculosis and other infectious
diseases in internationally adopted children CDC/TB Elimination Division:
Winthrop-University Hospital
Columbia University
Dr. Jane Aronson
TB and other Infections
504 children evaluated as outpatients at:
Winthrop-University Hospital Mineola, New York
1997-1998 |
| China |
243 |
| Russia |
155 |
| Other countries |
106 |
| Age range |
0-11.75 yrs |
| Mean age for total populatio |
1.61 yrs |
| Girls: 359 |
mean age: 1.46 yrs. |
| Boys: 145 |
mean age: 1.99 yrs. |
PPD Testing
- 404/504 children PPD tested 80.2%
- PPD read by healthcare provider
- China n=243
- 201/243=82.7%
- Russia n=155
- 133/155=85.8%
- Other n=106 70/106=66%
PPD Test Results
- 5-9 mm 23/404 5.7%
- >10 mm 73/404 18.1%
- China 5-9 mm 6/201 3%
- China > 10 mm 21/201 10.4%
- Russia 5-9 mm 13/133 9.8%
- Russia > 10 mm 39/133 29.3%
- Other > 10 mm 13/70 18.6%
PPD Test Results By Age
- # children > 1 year of age n=342
- 342/404=84.7%
- China n=166
- > 10 mm 19/166=11.5%
- Russia n=114
- > 10 mm 36/114=31.6%
- Children tested less than 1 year of age n=62
- 62/404=15.3%
- China n=35
- > 10 mm 2/35=5.7%
- Russia n=19
- > 10 mm 3/19=15.8%
BCG Data
- N=504
- 264/504 had BCG scars=52.4%
- 32 children additionally had record of BCG vaccine, but had no scar
- 296/504 exposed to BCG=58.7%
- 404 tested for TB, 220 with BCG evidence
- 220/404=54.5%
- 73 with positive skin tests (>10 mm)
- 64/73 (87.7%) had evidence of BCG
- China=20 Russia=34 Other=10
- Less than one year of age =7
- More than one year of age=57
- 39/73 (53.4%) were Russian children
Hepatitis B Data
- n=499 assessed for Hepatitis B
- 14 children were positive for Hep B surface antigen
- Hepatitis B carriage 14/499=2.8%
- China n=240
- 8/240 3.3%
- Russia n=153 4/153=2.6%
- N=499
- 240 Chinese children assessed for Hep B
- 80/240 (33.3%)Hep B surface antibody positive
- 15/80 (18.8%) record of Hep B vaccine
- 36/240 (15%) record of Hep B vaccine
- 160 Chinese adoptees were Hepatitis B surface antibody negative
- 21/160=13.1% record of Hep B vaccine
- 153 Russian children assessed for Hep B
- 22/153 (14.4%) Hepatitis B surface antibody positive
- 5/22 (22.7%) record of Hepatitis B vaccine
- 21/153 (13.7%) record of Hep B vaccine
- 131 children were Hepatitis B antibody negative
- 16/131 (12.2 %) record of Hep B vaccine
Hepatitis C Data
- N=916 assessed for Hepatitis C
- 6 children tested positive for Hepatitis C
- 6/916=0.66%
- 1 Moldova, 5 Russia
- 2 children are still pos for HCV antibody 2/916=0.22%, but are PCR
negative and one of these is RIBA negative
Syphilis Data
- RPR non-reactive, FTA-ABS positive
- N=478
- 11/478=2.3%
- 9 Russia, 1 Moldova, 1 Vietnam
- There were no children with acute infection
- Most recently we have 2 children w/acute syphilis 2/916=0.22%
Giardia Data
- N=461
- 94/461=20.4% were positive for Giardia antigen or cysts were found
in stool
- China 35/220=15.9%
- Russia 38/143=26.6%
- Other 21/98=21.4%
HIV Data
- N=490
- Two (2/490=0.41%) children from China were HIV ELISA positive
- Both children were PCR negative and were not infected
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